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Modulation of Obesity and Insulin Resistance by the Redox Enzyme and Adaptor Protein p66(Shc)
Initially reported as a longevity-related protein, the 66 kDa isoform of the mammalian Shc1 locus has been implicated in several metabolic pathways, being able to act both as an adaptor protein and as a redox enzyme capable of generating reactive oxygen species (ROS) when it localizes to the mitocho...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412263/ https://www.ncbi.nlm.nih.gov/pubmed/30813483 http://dx.doi.org/10.3390/ijms20040985 |