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Covalently Linking Oligomerization-Impaired GlpF Protomers Does Not Completely Re-establish Wild-Type Channel Activity

Integral membrane proteins of the aquaporin family facilitate rapid water flux across cellular membranes in all domains of life. Although the water-conducting pore is clearly defined in an aquaporin monomer, all aquaporins assemble into stable tetramers. In order to investigate the role of protomer–...

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Detalles Bibliográficos
Autores principales: Klein, Noreen, Trefz, Margareta, Schneider, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412381/
https://www.ncbi.nlm.nih.gov/pubmed/30791644
http://dx.doi.org/10.3390/ijms20040927