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Selective Inhibition of Human Monoamine Oxidase B by Acacetin 7-Methyl Ether Isolated from Turnera diffusa (Damiana)

The investigation of the constituents that were isolated from Turnera diffusa (damiana) for their inhibitory activities against recombinant human monoamine oxidases (MAO-A and MAO-B) in vitro identified acacetin 7-methyl ether as a potent selective inhibitor of MAO-B (IC(50) = 198 nM). Acacetin 7-me...

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Detalles Bibliográficos
Autores principales: Chaurasiya, Narayan D., Zhao, Jianping, Pandey, Pankaj, Doerksen, Robert J., Muhammad, Ilias, Tekwani, Babu L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412401/
https://www.ncbi.nlm.nih.gov/pubmed/30813423
http://dx.doi.org/10.3390/molecules24040810