The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neurons

Selenium application as sodium selenate was repeatedly shown to have anti-carcinogenic properties by increasing levels of the serine/ threonine protein phosphatase 2A (PP2A) in cancer cells. PP2A has a prominent role in cell development, homeostasis, and in neurons regulates excitability. PP2A, GSK3...

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Detalles Bibliográficos
Autores principales: Habbab, Wesal, Aoudé, Imad, Palangi, Freshteh, Abdulla, Sara, Ahmed, Tariq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412488/
https://www.ncbi.nlm.nih.gov/pubmed/30781361
http://dx.doi.org/10.3390/ijms20040844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412488/
https://www.ncbi.nlm.nih.gov/pubmed/30781361
http://dx.doi.org/10.3390/ijms20040844

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