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The Phenotype of Celiac Disease Has Low Concordance between Siblings, Despite a Similar Distribution of HLA Haplotypes

The factors determining the presentation of celiac disease are unclear. We investigated the phenotypic concordance and the distribution of human leukocyte antigen (HLA) risk haplotypes in affected siblings. One hundred sibling pairs were included. Clinical and histological parameters and HLA haploty...

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Detalles Bibliográficos
Autores principales: Kauma, Saana, Kaukinen, Katri, Huhtala, Heini, Kivelä, Laura, Pekki, Henna, Salmi, Teea, Saavalainen, Päivi, Lindfors, Katri, Kurppa, Kalle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412523/
https://www.ncbi.nlm.nih.gov/pubmed/30823533
http://dx.doi.org/10.3390/nu11020479