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The Combined Use of Phenothiazines and Statins Strongly Affects Doxorubicin-Resistance, Apoptosis, and Cox-2 Activity in Colon Cancer Cells

Since none of the multidrug resistance (MDR) modulators tested so far found their way into clinic, a novel approach to overcome the MDR of cancer cells has been proposed. The combined use of two MDR modulators of dissimilar mechanisms of action was suggested to benefit from the synergy between them....

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Detalles Bibliográficos
Autores principales: Środa-Pomianek, Kamila, Michalak, Krystyna, Palko-Łabuz, Anna, Uryga, Anna, Świątek, Piotr, Majkowski, Michał, Wesołowska, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412564/
https://www.ncbi.nlm.nih.gov/pubmed/30813251
http://dx.doi.org/10.3390/ijms20040955