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Polo-like kinase 4 promotes tumorigenesis and induces resistance to radiotherapy in glioblastoma

Glioblastoma (GBM) is one of the most malignant tumors in adults, associated with severe outcomes (median survival, <2 years). Multiple mechanisms are known to be involved in tumor recurrence and treatment resistance in GBM, however, the key regulator for GBM tumorigenesis and therapy resistance...

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Detalles Bibliográficos
Autores principales: Wang, Jia, Zuo, Jie, Wang, Maode, Ma, Xudong, Gao, Ke, Bai, Xiaobin, Wang, Ning, Xie, Wanfu, Liu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412581/
https://www.ncbi.nlm.nih.gov/pubmed/30816483
http://dx.doi.org/10.3892/or.2019.7012