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Myristica fragrans Kernels Prevent Paracetamol-Induced Hepatotoxicity by Inducing Anti-Apoptotic Genes and Nrf2/HO-1 Pathway

Paracetamol is responsible for acute liver failure in humans and experimental animals when taken at high doses and transformed into a reactive metabolite by the liver cytochrome P450. On the other hand, nutmeg is rich with many phytochemical ingredients that are known for their ability to inhibit cy...

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Detalles Bibliográficos
Autores principales: Dkhil, Mohamed A., Abdel Moneim, Ahmed E., Hafez, Taghreed A., Mubaraki, Murad A., Mohamed, Walid F., Thagfan, Felwa A., Al-Quraishy, Saleh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412641/
https://www.ncbi.nlm.nih.gov/pubmed/30823534
http://dx.doi.org/10.3390/ijms20040993