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Myristica fragrans Kernels Prevent Paracetamol-Induced Hepatotoxicity by Inducing Anti-Apoptotic Genes and Nrf2/HO-1 Pathway
Paracetamol is responsible for acute liver failure in humans and experimental animals when taken at high doses and transformed into a reactive metabolite by the liver cytochrome P450. On the other hand, nutmeg is rich with many phytochemical ingredients that are known for their ability to inhibit cy...
Autores principales: | Dkhil, Mohamed A., Abdel Moneim, Ahmed E., Hafez, Taghreed A., Mubaraki, Murad A., Mohamed, Walid F., Thagfan, Felwa A., Al-Quraishy, Saleh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412641/ https://www.ncbi.nlm.nih.gov/pubmed/30823534 http://dx.doi.org/10.3390/ijms20040993 |
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