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The Circadian tau Mutation in Casein Kinase 1 Is Part of a Larger Domain That Can Be Mutated to Shorten Circadian Period

Drosophila Double-time (DBT) phosphorylates the circadian protein Period (PER). The period-altering mutation tau, identified in hamster casein kinase I (CKIε) and created in Drosophila DBT, has been shown to shorten the circadian period in flies, as it does in hamsters. Since CKI often phosphorylate...

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Detalles Bibliográficos
Autores principales: Venkatesan, Anandakrishnan, Fan, Jin-Yuan, Bouyain, Samuel, Price, Jeffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412653/
https://www.ncbi.nlm.nih.gov/pubmed/30769795
http://dx.doi.org/10.3390/ijms20040813