Hydroxamic Acid-Based Histone Deacetylase (HDAC) Inhibitors Bearing a Pyrazole Scaffold and a Cinnamoyl Linker

Genetic abnormalities have been conventionally considered as hallmarks of cancer. However, recent studies have demonstrated that epigenetic mechanisms are also implicated in the insurgence and development of cancer. Patterns of the epigenetic component include DNA methylation and histone modificatio...

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Detalles Bibliográficos
Autores principales: Zagni, Chiara, Citarella, Andrea, Oussama, Mahjoub, Rescifina, Antonio, Maugeri, Alessandro, Navarra, Michele, Scala, Angela, Piperno, Anna, Micale, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412695/
https://www.ncbi.nlm.nih.gov/pubmed/30795625
http://dx.doi.org/10.3390/ijms20040945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412695/
https://www.ncbi.nlm.nih.gov/pubmed/30795625
http://dx.doi.org/10.3390/ijms20040945

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