A Novel Rare Missense Variation of the NOD2 Gene: Evidences of Implication in Crohn’s Disease

The NOD2 gene, involved in innate immune responses to bacterial peptidoglycan, has been found to be closely associated with Crohn’s Disease (CD), with an Odds Ratio ranging from 3–36. Families with three or more CD-affected members were related to a high frequency of NOD2 gene variations, such as R7...

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Detalles Bibliográficos
Autores principales: Frade-Proud’Hon-Clerc, Sara, Smol, Thomas, Frenois, Frédéric, Sand, Olivier, Vaillant, Emmanuel, Dhennin, Véronique, Bonnefond, Amélie, Froguel, Philippe, Fumery, Mathurin, Guillon-Dellac, Nathalie, Gower-Rousseau, Corinne, Vasseur, Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412783/
https://www.ncbi.nlm.nih.gov/pubmed/30769939
http://dx.doi.org/10.3390/ijms20040835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412783/
https://www.ncbi.nlm.nih.gov/pubmed/30769939
http://dx.doi.org/10.3390/ijms20040835

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