A Novel Dantrolene Sodium-Loaded Mixed Micelle Containing a Small Amount of Cremophor EL: Characterization, Stability, Safety and Pharmacokinetics

Dantrolene sodium (DS) is the only drug specifically used for the treatment of malignant hyperthermia. Nevertheless, its clinical application is significantly restricted due to its aqueous insolubility and the limited formulations available in clinical practice. In order to solve these problems, a n...

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Detalles Bibliográficos
Autores principales: Jin, Wenzhen, Tan, Xiaochuan, Wen, Jin, Meng, Ya, Zhang, Yujia, Li, He, Jiang, Dong, Song, Hui, Zheng, Wensheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412801/
https://www.ncbi.nlm.nih.gov/pubmed/30781606
http://dx.doi.org/10.3390/molecules24040728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412801/
https://www.ncbi.nlm.nih.gov/pubmed/30781606
http://dx.doi.org/10.3390/molecules24040728

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