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Synthesis, Characterization, and Biological Activity of a Novel Series of Benzo[4,5]imidazo[2,1-b]thiazole Derivatives as Potential Epidermal Growth Factor Receptor Inhibitors

Based on the analysis of epidermal growth factor receptor (EGFR) complexes with gefitinib with molecular docking, the scaffold-hopping strategy, combination of the active substructures, and structural optimization of EGFR inhibitors, a novel series of benzo[4,5]imidazo[2,1-b]thiazole derivatives was...

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Detalles Bibliográficos
Autores principales:	Deng, Xinshan, Tan, Xiaoyu, An, Tiantian, Ma, Qingqing, Jin, Zhe, Wang, Ce, Meng, Qingguo, Hu, Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412895/ https://www.ncbi.nlm.nih.gov/pubmed/30769844 http://dx.doi.org/10.3390/molecules24040682

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