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Intensive Distribution of G(2)-Quaduplexes in the Pseudorabies Virus Genome and Their Sensitivity to Cations and G-Quadruplex Ligands

Guanine-rich sequences in the genomes of herpesviruses can fold into G-quadruplexes. Compared with the widely-studied G(3)-quadruplexes, the dynamic G(2)-quadruplexes are more sensitive to the cell microenvironment, but they attract less attention. Pseudorabies virus (PRV) is the model species for t...

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Detalles Bibliográficos
Autores principales: Deng, Hui, Gong, Bowen, Yang, Zhiquan, Li, Zhen, Zhou, Huan, Zhang, Yashu, Niu, Xiaohui, Liu, Sisi, Wei, Dengguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412908/
https://www.ncbi.nlm.nih.gov/pubmed/30795541
http://dx.doi.org/10.3390/molecules24040774