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Loss of C/EBPδ Exacerbates Radiation-Induced Cognitive Decline in Aged Mice due to Impaired Oxidative Stress Response

Aging is characterized by increased inflammation and deterioration of the cellular stress responses such as the oxidant/antioxidant equilibrium, DNA damage repair fidelity, and telomeric attrition. All these factors contribute to the increased radiation sensitivity in the elderly as shown by epidemi...

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Detalles Bibliográficos
Autores principales: Banerjee, Sudip, Alexander, Tyler, Majumdar, Debajyoti, Groves, Thomas, Kiffer, Frederico, Wang, Jing, Gorantla, Akshita, Allen, Antiño R., Pawar, Snehalata A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412914/
https://www.ncbi.nlm.nih.gov/pubmed/30781689
http://dx.doi.org/10.3390/ijms20040885