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Further Probing of Cu(2+)-Dependent PNAzymes Acting as Artificial RNA Restriction Enzymes
Peptide nucleic acid (PNA)-neocuproine conjugates have been shown to efficiently catalyse the cleavage of RNA target sequences in the presence of Cu(2+) ions in a site-specific manner. These artificial enzymes are designed to force the formation of a bulge in the RNA target, the sequence of which ha...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412939/ https://www.ncbi.nlm.nih.gov/pubmed/30769777 http://dx.doi.org/10.3390/molecules24040672 |