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Quality Screening of Incorrectly Folded Soluble Aggregates from Functional Recombinant Proteins

Solubility is the prime criterion for determining the quality of recombinant proteins, yet it often fails to represent functional activity due to the involvement of non-functional, misfolded, soluble aggregates, which compromise the quality of recombinant proteins. However, guidelines for the qualit...

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Detalles Bibliográficos
Autores principales: Kwon, Soon Bin, Yu, Ji Eun, Kim, Jihoon, Oh, Hana, Park, Chan, Lee, Jinhee, Seong, Baik L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413200/
https://www.ncbi.nlm.nih.gov/pubmed/30791505
http://dx.doi.org/10.3390/ijms20040907