Microwave-Assisted Extraction of Multiple Trace Levels of Intermediate Metabolites for Camptothecin Biosynthesis in Camptotheca acuminata and Their Simultaneous Determination by HPLC-LTQ-Orbitrap-MS/MS and HPLC-TSQ-MS

Camptothecin (CPT) has strong antitumor activity and is used as an anticancer therapeutic agent. To better understand and decipher the pathway of CPT biosynthesis in Camptotheca acuminata, the main purpose here was focused on creating an effective extraction strategy for a rich intermediate metaboli...

Descripción completa

Detalles Bibliográficos
Autores principales: Jin, Zhaoxia, Wan, Ruyi, Yan, Ruxue, Su, Yingying, Huang, Honglan, Zi, Lihan, Yu, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413206/
https://www.ncbi.nlm.nih.gov/pubmed/30823523
http://dx.doi.org/10.3390/molecules24040815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413206/
https://www.ncbi.nlm.nih.gov/pubmed/30823523
http://dx.doi.org/10.3390/molecules24040815

Ejemplares similares