Cargando…

Microwave-Assisted Extraction of Multiple Trace Levels of Intermediate Metabolites for Camptothecin Biosynthesis in Camptotheca acuminata and Their Simultaneous Determination by HPLC-LTQ-Orbitrap-MS/MS and HPLC-TSQ-MS

Camptothecin (CPT) has strong antitumor activity and is used as an anticancer therapeutic agent. To better understand and decipher the pathway of CPT biosynthesis in Camptotheca acuminata, the main purpose here was focused on creating an effective extraction strategy for a rich intermediate metaboli...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jin, Zhaoxia, Wan, Ruyi, Yan, Ruxue, Su, Yingying, Huang, Honglan, Zi, Lihan, Yu, Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413206/ https://www.ncbi.nlm.nih.gov/pubmed/30823523 http://dx.doi.org/10.3390/molecules24040815

Ejemplares similares

Rapid Characterization and Identification of Non-Diterpenoid Constituents in Tinospora sinensis by HPLC-LTQ-Orbitrap MS(n)
por: Jiao, Qi-Shu, et al.
Publicado: (2018)

Chemical Profiling and Screening of the Marker Components in the Fruit of Cassia fistula by HPLC and UHPLC/LTQ-Orbitrap MS(n) with Chemometrics
por: Tan, Jiawei, et al.
Publicado: (2018)

Study on the Material Basis of Houpo Wenzhong Decoction by HPLC Fingerprint, UHPLC-ESI-LTQ-Orbitrap-MS, and Network Pharmacology
por: Luo, Juyuan, et al.
Publicado: (2019)

Simultaneous Analysis of Saccharides between Fresh and Processed Radix Rehmanniae by HPLC and UHPLC-LTQ-Orbitrap-MS with Multivariate Statistical Analysis
por: Xue, Shujuan, et al.
Publicado: (2018)

Using UPLC-LTQ-Orbitrap-MS and HPLC-CAD to Identify Impurities in Cycloastragenol, Which Is a Pre-Clinical Candidate for COPD
por: Zhu, Feng, et al.
Publicado: (2023)

The Tannins from Sanguisorba officinalis L. (Rosaceae): A Systematic Study on the Metabolites of Rats Based on HPLC–LTQ–Orbitrap MS(2) Analysis
por: Tu, Jingjing, et al.
Publicado: (2021)

Comprehensive Quality Assessment of Kaixin Powder by HPLC–DAD Quantification and HPLC–QTOF-MS/MS Confirmation
por: Wang, Binbin, et al.
Publicado: (2021)

Analysis of Chemical Constituents in Wuzi-Yanzong-Wan by UPLC-ESI-LTQ-Orbitrap-MS
por: Zou, Dixin, et al.
Publicado: (2015)

Identification of In Vivo Metabolites of Dictamnine in Mice Using HPLC-LTQ-Orbitrap Mass Spectrometry
por: Fu, Yudong, et al.
Publicado: (2018)

Determination of Florfenicol, Thiamfenicol and Chloramfenicol at Trace Levels in Animal Feed by HPLC–MS/MS
por: Gavilán, Rosa Elvira, et al.
Publicado: (2019)

Qualitative analysis of chemical components in Lianhua Qingwen capsule by HPLC-Q Exactive-Orbitrap-MS coupled with GC-MS
por: Fu, Shuai, et al.
Publicado: (2021)

Pyrosequencing of the Camptotheca acuminata transcriptome reveals putative genes involved in camptothecin biosynthesis and transport
por: Sun, Yongzhen, et al.
Publicado: (2011)

An ABCG-Type Transporter Facilitates ABA Influx and Regulates Camptothecin Biosynthesis in Camptotheca acuminata
por: Wang, Yanyan, et al.
Publicado: (2022)

Phenolic Profile of Grape Canes: Novel Compounds Identified by LC-ESI-LTQ-Orbitrap-MS
por: Escobar-Avello, Danilo, et al.
Publicado: (2019)

LC-ESI-LTQ-Orbitrap-MS for Profiling the Distribution of Oleacein and Its Metabolites in Rat Tissues
por: López-Yerena, Anallely, et al.
Publicado: (2021)

Phase II Metabolism of Asarone Isomers In Vitro and in Humans Using HPLC-MS/MS and HPLC-qToF/MS
por: Hermes, Lena, et al.
Publicado: (2021)

Determination of Oseltamivir in Human Plasma by HPLC-MS/MS
por: Lakeev, A. P., et al.
Publicado: (2023)

Extensive Thiol Profiling for Assessment of Intracellular Redox Status in Cultured Cells by HPLC-MS/MS
por: Wu, Jiandong, et al.
Publicado: (2021)

Corrigendum to “Identification of In Vivo Metabolites of Dictamnine in Mice Using HPLC-LTQ-Orbitrap Mass Spectrometry”
por: Fu, Yudong, et al.
Publicado: (2019)

Functional characterization of a catalytically promiscuous tryptophan decarboxylase from camptothecin-producing Camptotheca acuminata
por: Qiao, Chong, et al.
Publicado: (2022)

LC-ESI/LTQ-Orbitrap-MS Based Metabolomics in Evaluation of Bitter Taste of Arbutus unedo Honey
por: Montoro, Paola, et al.
Publicado: (2021)

HPLC-ESI-MS/MS of Imidazole Alkaloids in Pilocarpus microphyllus
por: Sawaya, Alexandra CH F, et al.
Publicado: (2008)

Development of an HPLC-MS/MS Method for the Determination of Alkaloids in Lupins
por: Eugelio, Fabiola, et al.
Publicado: (2023)

De novo genome assembly of Camptotheca acuminata, a natural source of the anti-cancer compound camptothecin
por: Zhao, Dongyan, et al.
Publicado: (2017)

Ultrasonic Assisted-Reflux Synergistic Extraction of Camptothecin and Betulinic Acid from Camptotheca acuminata Decne. Fruits
por: Li, Chunying, et al.
Publicado: (2017)

A chromosome-level Camptotheca acuminata genome assembly provides insights into the evolutionary origin of camptothecin biosynthesis
por: Kang, Minghui, et al.
Publicado: (2021)

Green Extraction of Alkaloids and Polyphenols from Peumus boldus Leaves with Natural Deep Eutectic Solvents and Profiling by HPLC-PDA-IT-MS/MS and HPLC-QTOF-MS/MS
por: Torres-Vega, Jeniffer, et al.
Publicado: (2020)

An integrated strategy for quality control of the multi-origins herb medicine of Gentianae Macrophyllae Radix based on UPLC-Orbitrap-MS/MS and HPLC-DAD
por: Luo, Jiangyi, et al.
Publicado: (2023)

Identification of volatile and nonvolatile compounds in Citri Reticulatae Pericarpium Viride using GC–MS, UPLC‐Q‐Exactive Orbitrap‐MS, and HPLC‐PDA
por: Li, Jingxuan, et al.
Publicado: (2023)

Development Rapid Analytical Methods for Inositol as a Trace Component by HPLC and LC-MS/MS in Infant Formula
por: Shin, Jin-Ho, et al.
Publicado: (2015)

In Vivo Metabolite Profiling of DMU-212 in Apc(Min/+) Mice Using UHPLC-Q/Orbitrap/LTQ MS
por: Li, Jing, et al.
Publicado: (2023)

Development and Validation of an HPLC-MS/MS Method for the Early Diagnosis of Aspergillosis
por: Cerqueira, Letícia B., et al.
Publicado: (2014)

HPLC-MS/MS Method for the Measurement of Insecticide Degradates in Baby Food
por: Radford, Samantha A., et al.
Publicado: (2014)

Determination of Glyphosate in White and Brown Rice with HPLC-ICP-MS/MS
por: Fontanella, Maria Chiara, et al.
Publicado: (2022)

Analysis of 3‐nitropropionic acid in Fabaceae plants by HPLC‐MS/MS
por: Takács, Orsolya, et al.
Publicado: (2022)

Integrative Analysis of Elicitor-Induced Camptothecin Biosynthesis in Camptotheca acuminata Plantlets Through a Combined Omics Approach
por: Pu, Xiang, et al.
Publicado: (2022)

Cleaning up the masses: Exclusion lists to reduce contamination with HPLC-MS/MS()
por: Hodge, Kelly, et al.
Publicado: (2013)

Development and validation of an HPLC–MS/MS method to determine clopidogrel in human plasma
por: Liu, Gangyi, et al.
Publicado: (2016)

Analysis of Tetracyclines in Medicated Feed for Food Animal Production by HPLC-MS/MS
por: Gavilán, Rosa Elvira, et al.
Publicado: (2015)

Diagnostic accuracy of thromboelastometry and its correlation with the HPLC-MS/MS quantification test
por: de Aranda, V.F., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_7r0ccd08vvqb9ookh9cglirnjt