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hCMV-Mediated Immune Escape Mechanisms Favor Pathogen Growth and Disturb the Immune Privilege of the Eye

Human retinal pigment epithelial (hRPE) cells are important for the establishment and maintenance of the immune privilege of the eye. They function as target cells for human cytomegalovirus (hCMV), but are able to restrict viral replication. hCMV causes opportunistic posterior uveitis such as retini...

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Detalles Bibliográficos
Autores principales: Spekker-Bosker, Katrin, Ufermann, Christoph-Martin, Maywald, Marco, Zimmermann, Albert, Domröse, Andreas, Woite, Claudia, Däubener, Walter, Eller, Silvia Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413209/
https://www.ncbi.nlm.nih.gov/pubmed/30781494
http://dx.doi.org/10.3390/ijms20040858