Genotypic and Phenotypic Variables Affect Meiotic Cell Cycle Progression, Tumor Ploidy, and Cancer-Associated Mortality in a brca2-Mutant Zebrafish Model

Successful cell replication requires both cell cycle completion and accurate chromosomal segregation. The tumor suppressor BRCA2 is positioned to influence both of these outcomes, and thereby influence genomic integrity, during meiotic and mitotic cell cycles. Accordingly, mutations in BRCA2 induce...

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Detalles Bibliográficos
Autores principales: Mensah, L., Ferguson, J. L., Shive, H. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413366/
https://www.ncbi.nlm.nih.gov/pubmed/30930946
http://dx.doi.org/10.1155/2019/9218251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413366/
https://www.ncbi.nlm.nih.gov/pubmed/30930946
http://dx.doi.org/10.1155/2019/9218251

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