A Clinically Applicable Positive Allosteric Modulator of GABA Receptors Promotes Human β-Cell Replication and Survival as well as GABA's Ability to Inhibit Inflammatory T Cells

A major goal of T1D research is to develop new approaches to increase β-cell mass and control autoreactive T cell responses. GABA(A)-receptors (GABA(A)-Rs) are promising drug targets in both those regards due to their abilities to promote β-cell replication and survival, as well as inhibit autoreact...

Descripción completa

Detalles Bibliográficos
Autores principales: Tian, Jide, Dang, Hoa, Karashchuk, Nataliya, Xu, Irvin, Kaufman, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413367/
https://www.ncbi.nlm.nih.gov/pubmed/30937314
http://dx.doi.org/10.1155/2019/5783545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413367/
https://www.ncbi.nlm.nih.gov/pubmed/30937314
http://dx.doi.org/10.1155/2019/5783545

Ejemplares similares