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A Clinically Applicable Positive Allosteric Modulator of GABA Receptors Promotes Human β-Cell Replication and Survival as well as GABA's Ability to Inhibit Inflammatory T Cells
A major goal of T1D research is to develop new approaches to increase β-cell mass and control autoreactive T cell responses. GABA(A)-receptors (GABA(A)-Rs) are promising drug targets in both those regards due to their abilities to promote β-cell replication and survival, as well as inhibit autoreact...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413367/ https://www.ncbi.nlm.nih.gov/pubmed/30937314 http://dx.doi.org/10.1155/2019/5783545 |