NOTCH Signaling Is Activated through Mechanical Strain in Human Bone Marrow-Derived Mesenchymal Stromal Cells

Skeletal development and remodeling of adult bone are critically controlled by activated NOTCH signaling in genetically modified mice. It is yet unclear whether NOTCH signaling is activated by mechanical strain sensed by bone cells. We found that expression of specific NOTCH target genes is induced...

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Detalles Bibliográficos
Autores principales: Ziouti, Fani, Ebert, Regina, Rummler, Maximilian, Krug, Melanie, Müller-Deubert, Sigrid, Lüdemann, Martin, Jakob, Franz, Willie, Bettina M., Jundt, Franziska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413410/
https://www.ncbi.nlm.nih.gov/pubmed/30936923
http://dx.doi.org/10.1155/2019/5150634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413410/
https://www.ncbi.nlm.nih.gov/pubmed/30936923
http://dx.doi.org/10.1155/2019/5150634

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