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Differential Effects of the Absence of Nkx2-3 and MAdCAM-1 on the Distribution of Intestinal Type 3 Innate Lymphoid Cells and Postnatal SILT Formation in Mice

Seeding of leukocytes to developing lymphoid tissues in embryonic and early postnatal age and to the mucosa throughout adulthood depends on the interaction between endothelial MAdCAM-1 addressin and its cognate ligand α4β7 integrin. Nkx2-3 as a transcriptional regulator of MAdCAM-1 controls vascular...

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Detalles Bibliográficos
Autores principales: Vojkovics, Dóra, Kellermayer, Zoltán, Gábris, Fanni, Schippers, Angela, Wagner, Norbert, Berta, Gergely, Farkas, Kornélia, Balogh, Péter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413488/
https://www.ncbi.nlm.nih.gov/pubmed/30891037
http://dx.doi.org/10.3389/fimmu.2019.00366