Direct modification of spermatogonial stem cells using lentivirus vectors in vivo leads to efficient generation of transgenic rats

Spermatogonial stem cells (SSCs) transmit genetic information to the next progeny in males. Thus, SSCs are a potential target for germline modifications to generate transgenic animals. In this study, we report a technique for the generation of transgenic rats by in vivo manipulation of SSCs with a h...

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Detalles Bibliográficos
Autores principales: Kim, Bang-Jin, Kim, Yong-Hee, Oh, Myeong-Geun, Kim, Ki-Jung, Jung, Sang-Eun, Jin, Ju-Hee, Kim, Sun-Uk, Min, Kwan-Sik, Ryu, Buom-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413556/
https://www.ncbi.nlm.nih.gov/pubmed/30319135
http://dx.doi.org/10.4103/aja.aja_80_18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413556/
https://www.ncbi.nlm.nih.gov/pubmed/30319135
http://dx.doi.org/10.4103/aja.aja_80_18

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