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Toll-like receptor 2 and Toll-like receptor 4 exhibit distinct regulation of cancer cell stemness mediated by cell death-induced high-mobility group box 1

BACKGROUND: High-mobility group box 1 (HMGB1), a common extracellular damage associated molecular pattern molecule, is overexpressed in several solid tumors including pancreatic carcinoma. We previously observed that radiotherapy induced dying cells secrete HMGB1 and accelerate pancreatic carcinoma...

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Detalles Bibliográficos
Autores principales: Chen, Xuelian, Cheng, Fang, Liu, Yanfang, Zhang, Lirong, Song, Lian, Cai, Xiaojie, You, Tao, Fan, Xin, Wang, Dongqing, Gong, Aihua, Zhu, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413584/
https://www.ncbi.nlm.nih.gov/pubmed/30679086
http://dx.doi.org/10.1016/j.ebiom.2018.12.016