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HIF1α‐mediated AIMP3 suppression delays stem cell aging via the induction of autophagy

Senescence in stem cells, which occurs as a consequence of chronic responses to the environment, defines the capacity of stem cells for proliferation and differentiation as well as their potential for tissue regeneration and homeostasis maintenance. Although stem cells reside under low oxygen pressu...

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Detalles Bibliográficos
Autores principales: Kim, Chul, Park, Ji‐Min, Song, Youngsook, Kim, Sunghoon, Moon, Jisook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413650/
https://www.ncbi.nlm.nih.gov/pubmed/30706629
http://dx.doi.org/10.1111/acel.12909