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Dietary restriction and gonadal signaling differentially regulate post‐development quality control functions in Caenorhabditis elegans
Protein homeostasis is remodeled early in Caenorhabditis elegans adulthood, resulting in a sharp decline in folding capacity and reduced ability to cope with chronic and acute stress. Endocrine signals from the reproductive system can ameliorate this proteostatic collapse and reshape the quality con...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413660/ https://www.ncbi.nlm.nih.gov/pubmed/30648346 http://dx.doi.org/10.1111/acel.12891 |