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Dietary restriction and gonadal signaling differentially regulate post‐development quality control functions in Caenorhabditis elegans

Protein homeostasis is remodeled early in Caenorhabditis elegans adulthood, resulting in a sharp decline in folding capacity and reduced ability to cope with chronic and acute stress. Endocrine signals from the reproductive system can ameliorate this proteostatic collapse and reshape the quality con...

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Detalles Bibliográficos
Autores principales: Shpigel, Nufar, Shemesh, Netta, Kishner, Mor, Ben‐Zvi, Anat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413660/
https://www.ncbi.nlm.nih.gov/pubmed/30648346
http://dx.doi.org/10.1111/acel.12891