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Activation of MT2 receptor ameliorates dendritic abnormalities in Alzheimer’s disease via C/EBPα/miR‐125b pathway

Impairments of dendritic trees and spines have been found in many neurodegenerative diseases, including Alzheimer's disease (AD), in which the deficits of melatonin signal pathway were reported. Melatonin receptor 2 (MT2) is widely expressed in the hippocampus and mediates the biological functi...

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Detalles Bibliográficos
Autores principales: Tang, Hui, Ma, Mei, Wu, Ying, Deng, Man‐Fei, Hu, Fan, Almansoub, Hasan.a.m.m., Huang, He‐Zhou, Wang, Ding‐Qi, Zhou, Lan‐Ting, Wei, Na, Man, Hengye, Lu, Youming, Liu, Dan, Zhu, Ling‐Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413662/
https://www.ncbi.nlm.nih.gov/pubmed/30706990
http://dx.doi.org/10.1111/acel.12902