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Inhibition of nucleolar stress response by Sirt1: A potential mechanism of acetylation‐independent regulation of p53 accumulation

The mammalian Sirt1 deacetylase is generally thought to be a nuclear protein, but some pilot studies have suggested that Sirt1 may also be involved in orchestrating nucleolar functions. Here, we show that nucleolar stress response is a ubiquitous cellular reaction that can be induced by different ty...

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Detalles Bibliográficos
Autores principales: Bi, Xiaolei, Ye, Qing, Li, Daoyuan, Peng, Qisheng, Wang, Zhe, Wu, Xiao, Zhang, Yun, Zhang, Qunye, Jiang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413664/
https://www.ncbi.nlm.nih.gov/pubmed/30623565
http://dx.doi.org/10.1111/acel.12900