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HLA-C-restricted viral epitopes are associated with an escape mechanism from KIR2DL2(+) NK cells in Lassa virus infection

BACKGROUND: Lassa virus (LASV) is the etiologic agent of an acute hemorrhagic fever endemic in West Africa. Natural killer (NK) cells control viral infections in part through the interaction between killer cell immunoglobulin-like receptors (KIRs) and their ligands. LASV infection is associated with...

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Detalles Bibliográficos
Autores principales: Wauquier, Nadia, Petitdemange, Caroline, Tarantino, Nadine, Maucourant, Christopher, Coomber, Moinya, Lungay, Victor, Bangura, James, Debré, Patrice, Vieillard, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413685/
https://www.ncbi.nlm.nih.gov/pubmed/30711514
http://dx.doi.org/10.1016/j.ebiom.2019.01.048