sFRP3 inhibition improves age‐related cellular changes in BubR1 progeroid mice

Wnt signaling is a well‐known molecular pathway in age‐related pathogenesis and therapy of disease. While prior studies have mainly focused on Wnt ligands or Wnt activators, the in vivo functions of naturally secreted Wnt inhibitors are not clear, especially in brain aging. Using BubR1 (H/H) mice as...

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Detalles Bibliográficos
Autores principales: Cho, Chang Hoon, Yoo, Ki Hyun, Oliveros, Alfredo, Paulson, Summer, Hussaini, Syed Mohammed Qasim, van Deursen, Jan M., Jang, Mi‐Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Short Take
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413750/
https://www.ncbi.nlm.nih.gov/pubmed/30609266
http://dx.doi.org/10.1111/acel.12899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413750/
https://www.ncbi.nlm.nih.gov/pubmed/30609266
http://dx.doi.org/10.1111/acel.12899

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