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A novel strategy of transferring NIS protein to cells using extracellular vesicles leads to increase in iodine uptake and cytotoxicity

BACKGROUND: This study was designed to explore a novel approach for transferring NIS protein to cells using extracellular vesicle (EV) and enhancing iodine avidity in hepatocellular carcinoma (HCC) cells. METHODS: We transfected the HCC cells (Huh7) with NIS gene, designated as Huh7/NIS, and isolate...

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Detalles Bibliográficos
Autores principales: Son, Seung Hyun, Gangadaran, Prakash, Ahn, Byeong-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413815/
https://www.ncbi.nlm.nih.gov/pubmed/30880979
http://dx.doi.org/10.2147/IJN.S189738