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A novel strategy of transferring NIS protein to cells using extracellular vesicles leads to increase in iodine uptake and cytotoxicity
BACKGROUND: This study was designed to explore a novel approach for transferring NIS protein to cells using extracellular vesicle (EV) and enhancing iodine avidity in hepatocellular carcinoma (HCC) cells. METHODS: We transfected the HCC cells (Huh7) with NIS gene, designated as Huh7/NIS, and isolate...
Autores principales: | Son, Seung Hyun, Gangadaran, Prakash, Ahn, Byeong-Cheol |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413815/ https://www.ncbi.nlm.nih.gov/pubmed/30880979 http://dx.doi.org/10.2147/IJN.S189738 |
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