Clinical validation of an evidence-based method to adjust Pancreatic Enzyme Replacement Therapy through a prospective interventional study in paediatric patients with Cystic Fibrosis

BACKGROUND: A method to adjust Pancreatic Enzyme Replacement Therapy in Cystic Fibrosis is not currently available. OBJECTIVES: To assess the in vivo efficacy of a method to adjust the dose of enzymatic supplement in CF extrapolated from previous in vitro digestion studies (theoretical optimal dose,...

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Detalles Bibliográficos
Autores principales: Calvo-Lerma, Joaquim, Hulst, Jessie, Boon, Mieke, Colombo, Carla, Masip, Etna, Ruperto, Mar, Fornés-Ferrer, Victoria, van der Wiel, Els, Claes, Ine, Garriga, Maria, Roca, Maria, Crespo-Escobar, Paula, Bulfamante, Anna, Woodcock, Sandra, Martínez-Barona, Sandra, Andrés, Ana, de Boeck, Kris, Ribes-Koninckx, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413926/
https://www.ncbi.nlm.nih.gov/pubmed/30861039
http://dx.doi.org/10.1371/journal.pone.0213216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413926/
https://www.ncbi.nlm.nih.gov/pubmed/30861039
http://dx.doi.org/10.1371/journal.pone.0213216

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