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The selective autophagy receptors Optineurin and p62 are both required for zebrafish host resistance to mycobacterial infection

Mycobacterial pathogens are the causative agents of chronic infectious diseases like tuberculosis and leprosy. Autophagy has recently emerged as an innate mechanism for defense against these intracellular pathogens. In vitro studies have shown that mycobacteria escaping from phagosomes into the cyto...

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Detalles Bibliográficos
Autores principales: Zhang, Rui, Varela, Monica, Vallentgoed, Wies, Forn-Cuni, Gabriel, van der Vaart, Michiel, Meijer, Annemarie H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413957/
https://www.ncbi.nlm.nih.gov/pubmed/30818338
http://dx.doi.org/10.1371/journal.ppat.1007329