Synovium extra cellular matrices seeded with transduced mesenchymal stem cells stimulate chondrocyte maturation in vitro and cartilage healing in clinically-induced rat-knee lesions in vivo

Osteoarthritis (OA) is a progressive disease associated with cartilage injury and its inherently limited repair capability. Synovium-based cellular constructs (sConstructs) are proposed as possible treatments. Equine sConstructs were produced from decellularized synovium-based extracellular matrix s...

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Detalles Bibliográficos
Autores principales: Reisbig, Nathalie A., Pinnell, Erin, Scheuerman, Logan, Hussein, Hayam, Bertone, Alicia L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414009/
https://www.ncbi.nlm.nih.gov/pubmed/30861010
http://dx.doi.org/10.1371/journal.pone.0212664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414009/
https://www.ncbi.nlm.nih.gov/pubmed/30861010
http://dx.doi.org/10.1371/journal.pone.0212664

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