Dynamic Ligand Discrimination in the Notch Signaling Pathway

The Notch signaling pathway comprises multiple ligands that are used in distinct biological contexts. In principle, different ligands could activate distinct target programs in signal-receiving cells, but it is unclear how such ligand discrimination could occur. Here, we show that cells use dynamics...

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Detalles Bibliográficos
Autores principales: Nandagopal, Nagarajan, Santat, Leah A., LeBon, Lauren, Sprinzak, David, Bronner, Marianne E., Elowitz, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414217/
https://www.ncbi.nlm.nih.gov/pubmed/29398116
http://dx.doi.org/10.1016/j.cell.2018.01.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414217/
https://www.ncbi.nlm.nih.gov/pubmed/29398116
http://dx.doi.org/10.1016/j.cell.2018.01.002

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