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Dynamic Ligand Discrimination in the Notch Signaling Pathway
The Notch signaling pathway comprises multiple ligands that are used in distinct biological contexts. In principle, different ligands could activate distinct target programs in signal-receiving cells, but it is unclear how such ligand discrimination could occur. Here, we show that cells use dynamics...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414217/ https://www.ncbi.nlm.nih.gov/pubmed/29398116 http://dx.doi.org/10.1016/j.cell.2018.01.002 |