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A Genome-wide Association and Admixture Mapping Study of Bronchodilator Drug Response in African Americans with Asthma

Short-acting β(2)-adrenergic receptor agonists (SABAs) are the most commonly prescribed asthma medications worldwide. Response to SABAs is measured as bronchodilator drug response (BDR), which varies among racial/ethnic groups in the U.S(1, 2). However, the genetic variation that contributes to BDR...

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Detalles Bibliográficos
Autores principales: Spear, Melissa L., Hu, Donglei, Pino-Yanes, Maria, Huntsman, Scott, Eng, Celeste, Levin, Albert M., Ortega, Victor E., White, Marquitta J., McGarry, Meghan E., Thakur, Neeta, Galanter, Joshua, Mak, Angel C.Y., Oh, Sam S., Ampleford, Elizabeth, Peters, Stephen P., Davis, Adam, Kumar, Rajesh, Farber, Harold J., Meade, Kelley, Avila, Pedro C., Serebrisky, Denise, Lenoir, Michael A., Brigino-Buenaventura, Emerita, Cintron, William Rodriguez, Thyne, Shannon M., Rodriguez-Santana, Jose R., Ford, Jean G., Chapela, Rocio, Estrada, Andrés Moreno, Sandoval, Karla, Seibold, Max A., Winkler, Cheryl A., Bleecker, Eugene R., Myers, Deborah A., Keoki Williams, L., Hernandez, Ryan D., Torgerson, Dara G., Burchard, Esteban G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414286/
https://www.ncbi.nlm.nih.gov/pubmed/30206298
http://dx.doi.org/10.1038/s41397-018-0042-4