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Dynamic blebbing: A bottleneck to human embryonic stem cell culture that can be overcome by Laminin-Integrin signaling

This study characterizes dynamic and apoptotic blebbing in human embryonic stem cells (hESC), identifies dynamic blebbing as a bottleneck to successful cell attachment during passaging, and demonstrates that dynamic blebbing can be rapidly stopped by plating cells on recombinant human laminin. In fr...

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Detalles Bibliográficos
Autores principales: Weng, Nikki Jo-Hao, Cheung, Cindy, Talbot, Prue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414319/
https://www.ncbi.nlm.nih.gov/pubmed/30458343
http://dx.doi.org/10.1016/j.scr.2018.10.022