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Validation of a Bioinformatics Workflow for Routine Analysis of Whole-Genome Sequencing Data and Related Challenges for Pathogen Typing in a European National Reference Center: Neisseria meningitidis as a Proof-of-Concept

Despite being a well-established research method, the use of whole-genome sequencing (WGS) for routine molecular typing and pathogen characterization remains a substantial challenge due to the required bioinformatics resources and/or expertise. Moreover, many national reference laboratories and cent...

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Detalles Bibliográficos
Autores principales: Bogaerts, Bert, Winand, Raf, Fu, Qiang, Van Braekel, Julien, Ceyssens, Pieter-Jan, Mattheus, Wesley, Bertrand, Sophie, De Keersmaecker, Sigrid C. J., Roosens, Nancy H. C., Vanneste, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414443/
https://www.ncbi.nlm.nih.gov/pubmed/30894839
http://dx.doi.org/10.3389/fmicb.2019.00362