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Plasma alpha‐synuclein detected by single molecule array is increased in PD

We utilized ultrasensitive single molecule technology to measure plasma alpha‐synuclein in 221 subjects (51 controls, 170 PD). Plasma alpha‐synuclein levels were significantly higher in PD than controls (15506.3 vs. 13057.0 pg/mL, P = 0.037), adjusting for age and gender. In PD, alpha‐synuclein leve...

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Detalles Bibliográficos
Autores principales: Ng, Adeline S. L., Tan, Yi Jayne, Lu, Zhonghao, Ng, Ebonne Y. L., Ng, Samuel Y. E., Chia, Nicole S. Y., Setiawan, Fiona, Xu, Zheyu, Tay, Kay Yaw, Prakash, Kumar M., Au, Wing Lok, Tan, Eng‐King, Tan, Louis C. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414476/
https://www.ncbi.nlm.nih.gov/pubmed/30911585
http://dx.doi.org/10.1002/acn3.729