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CRIS.py: A Versatile and High-throughput Analysis Program for CRISPR-based Genome Editing

CRISPR-Cas9 technology allows the creation of user-defined genomic modifications in cells and whole organisms. However, quantifying editing rates in pools of cells or identifying correctly edited clones is tedious. Targeted next-generation sequencing provides a high-throughput platform for optimizin...

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Detalles Bibliográficos
Autores principales: Connelly, Jon P., Pruett-Miller, Shondra M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414496/
https://www.ncbi.nlm.nih.gov/pubmed/30862905
http://dx.doi.org/10.1038/s41598-019-40896-w