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Glatiramer Acetate modulates ion channels expression and calcium homeostasis in B cell of patients with relapsing-remitting multiple sclerosis

To investigate the effects of Glatiramer Acetate (GA) on B cells by an integrated computational and experimental approach. GA is an immunomodulatory drug approved for the treatment of multiple sclerosis (MS). GA effect on B cells is yet to be fully elucidated. We compared transcriptional profiles of...

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Detalles Bibliográficos
Autores principales: Criscuolo, C., Cianflone, A., Lanzillo, R., Carrella, D., Carissimo, A., Napolitano, F., de Cegli, R., de Candia, P., La Rocca, C., Petrozziello, T., Matarese, G., Boscia, F., Secondo, A., Di Bernardo, D., Brescia Morra, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414512/
https://www.ncbi.nlm.nih.gov/pubmed/30862866
http://dx.doi.org/10.1038/s41598-018-38152-8