CryoEM structure of adenovirus type 3 fibre with desmoglein 2 shows an unusual mode of receptor engagement

Attachment of human adenovirus (HAd) to the host cell is a critical step of infection. Initial attachment occurs via the adenoviral fibre knob protein and a cellular receptor. Here we report the cryo-electron microscopy (cryo-EM) structure of a <100 kDa non-symmetrical complex comprising the trim...

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Detalles Bibliográficos
Autores principales: Vassal-Stermann, Emilie, Effantin, Gregory, Zubieta, Chloe, Burmeister, Wim, Iseni, Frédéric, Wang, Hongjie, Lieber, André, Schoehn, Guy, Fender, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414520/
https://www.ncbi.nlm.nih.gov/pubmed/30862836
http://dx.doi.org/10.1038/s41467-019-09220-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414520/
https://www.ncbi.nlm.nih.gov/pubmed/30862836
http://dx.doi.org/10.1038/s41467-019-09220-y

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