PTMselect: optimization of protein modifications discovery by mass spectrometry

Discovery of protein modification sites relies on protein digestion by proteases and mass spectrometry (MS) identification of the modified peptides. Depending on proteases used and target protein sequence, this method yields highly variable coverage of modification sites. We introduce PTMselect, a d...

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Detalles Bibliográficos
Autores principales: Perchey, Renaud T., Tonini, Laure, Tosolini, Marie, Fournié, Jean-Jacques, Lopez, Frédéric, Besson, Arnaud, Pont, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414543/
https://www.ncbi.nlm.nih.gov/pubmed/30862887
http://dx.doi.org/10.1038/s41598-019-40873-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414543/
https://www.ncbi.nlm.nih.gov/pubmed/30862887
http://dx.doi.org/10.1038/s41598-019-40873-3

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