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PTMselect: optimization of protein modifications discovery by mass spectrometry
Discovery of protein modification sites relies on protein digestion by proteases and mass spectrometry (MS) identification of the modified peptides. Depending on proteases used and target protein sequence, this method yields highly variable coverage of modification sites. We introduce PTMselect, a d...
Autores principales: | Perchey, Renaud T., Tonini, Laure, Tosolini, Marie, Fournié, Jean-Jacques, Lopez, Frédéric, Besson, Arnaud, Pont, Frédéric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414543/ https://www.ncbi.nlm.nih.gov/pubmed/30862887 http://dx.doi.org/10.1038/s41598-019-40873-3 |
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